As pointed out all LT225/75R-16 tires have to meet the tire safety tests, which are covered by NHTSA FMVSS 139:
http://www.nhtsa.gov/DOT/NHTSA/Vehicle%20Safety/Test%20Procedures/Associated%20Files/TP-139-02.pdfThis covers such tests as tire endurance, puncture resistance, running under inflated, etc.
What the tests do not tell you is how much design margin the tires have, the tires are not stressed to failure and results reported.
The tires vary in weight, for example an LTX M/S2 tire weighs 39 lbs per tire, and an XPS Rib weighs 49 lbs. per tire. I take tire weight to be a proxy for design margin and that is why I have all steel cased tires.
Another choice for all-steel cased tires with M/S capability is the Goodyear G947 RSS Armor Max.