We have traveled with 2 cats in both a MH and a travel trailer. We did not have great luck with them in the MH because of all the motion. With the trailer we fold up the back seats of the Tundra and place a large mesh enclosure on the floor, with blankets and a disposable litter pan we get at the grocery. They don't usually use the litter pan except when we are stopped. Then it's easy to clean it before we take off. Only once did we have a cat use the litter pan underway. They settle right down after we leave and move around periodically, but otherwise are content to stay put on their blanket. When we are all set up at the campsite, we put a leash on their harnesses (which they wear when we travel), take them into the camper and then let them settle in.