Daytime, between the Appalachian mountains and the Sierra Nevada. Part of my reason for daytime is availability of services, part has to do with the fact that automotive lighting is grossly inadequate for night time driving at highway speeds common in the U.S. so that everybody is over-driving their headlights and hoping the hazards they can't see are not actually there.
I have to adjust for travel, because when I'm not traveling most of my awake hours are at night.