I have been running multiple 12VDC batteries in my OFF-ROAD POPUP setup since 2009. My trailer came with two each standard issue GP24 12VDC Interstate Deep Cycle batteries. I added wring for two additional 12VDC batteries but only installed one as the 255Ah capacity was allowing me to camp off the power grid like we was wanting to do. Just never added the fourth Interstate battery.
I also added a new smart mode PD9260C 60 AMP converter/charger unit so that I could connect my trailer 30AMP Shore Power cable using a RV30A-15A adapter to my 2KW Honda Generator 120VAC Receptacle at 8AM each morning and recharge my three 12VDC Interstate batteries to their 90% charge state in a short three hour generator run time period.
Been doing this since 2009 and we are very successful camping off the power grid running some 120VAC items from an 600WATT PSW Inverter and many other 12VDC item direct connected to the three 12VDC batteries.
All of this took some planning so that my three batteries would be at the 12.0VDC level at 8AM each morning which is approximately the 50% charge state. My three batteries are still going great since 2009 and are just now staring to show some drop in performance. I am planning to start replacing them this season.
My real success was being able to monitor my batteries operations inside my trailer using a BATTERY MONITOR DC METER setup I can tell at a glance my approximate BATTERY BANK CHARGE STATUS using the chart. With my DC Monitor Panel I usually see around 52-53AMPS DC when in boost 14.4VDC charge mode for around 15-20 minutes and then it starts dropping back to around 8AMP after two hours of charge. Then the PD9260C will drop back to its 13.6VDC charge mode and my DC current drops down to around 6AMPS of charge for the remaining one more hour of charging.

This is a photo and diagram of my setup to support the additional 12VDC batteries mounted on the trailer frame between the Propane tanks and the front trailer deck. The batteries are sitting on a 1X1 metal angle strip going across the top of the frame extending out on both side as shown. With a longer angle strip this would support four batteries easily.

Since my original WFCO WF8945 converter/charger was new I elected to add my PD9260C 60AMP converter/charger in series with the 4AWG cables feeding the battery switches. This is a backup as I can just flip the 120VAC Circuit breaker to power up the converter/charger unit I want to use. I could never get my WFCO WF8945 45AMP converter/charger to go into smart mode charging so it is just used as a backup to give 45AMPS capacity of 13.6VDC if needed. This allowed me to install my PD9260C 60AMP converter/charger stand alone much closer to the battery switches. I am using a 600WATT PSW Inverter verses the 1500WATT PSW shown in the diagram..

Note using the BLUE SEA 4-position Battery switches allows me complete control of which batteries are selected for use. This also allowed me to use same length battery cables to help keep the DC current flow as close as possible in operation. The three Blue Sea switches also provides a complete disconnect of all batteries when placed in the OFF position.

My 12VDC Battery hookup
Roy Ken