The answer depends on your converter.. If you have a good quality 3-stage + converter such as a Progressive Dynamics charge wizard unit or an Iota with IQ-4, Leave it connected.. That is how I did it when this rig was new and the batteries lasted 4 years that way and five more full timing it. (9 total) Before we went full time I only added distilled water on Mother's day.
IF, on the other hand you have a low end single stage.. Well, Some of those tend to overcharge, some undercharge, none do it right.
I would hope a 50 amp rig has a good 3-stage.