I am wary of using them on a multi-axle trailer due to the forces on the sidewalls, but on a single axle you really only need to worry about sufficient weight capacity and choosing a tread that will track well.
If the bolt pattern is a common size and you have sufficient fender clearance, you might think about going up in tire diameter and capacity in one of the stock trailer wheel sizes.
My enclosed trailer used four LRD 15" tires and when they wore out I went with the same size LRE to give me better wear and puncture resistance. If I didn't find these ST tires, I was going to use a taller tire with more capacity but had to be careful to go too tall and rub when under load.
