When we were living in our 5th wheel fulltime I took my sewing machine with me. I put all my sewing supplies in a large tackle box. I actually bought a new machine while we were in the RV...a Janome which I still have and use a lot. I plan to take it with me when we return to fulltiming next year.
I used it for all kinds of projects: I love to do sewing crafts and make tote bags, purses, zippered pouches etc for my granddaughters. I make dog clothes (my girls get a new dress every holiday; tablecloths for each season (we replaced our table with a round drop leaf table) as well as for repairs etc. It is kept under our bed and doesn't take up much room. I have a small ironing board and iron too, used mainly when I'm crafting.
Sometimes I would sew outside on the patio with a folding table we keep in the basement, and other times I'd use the dining room table.
If you enjoy sewing I would definitely take it with you.