This is an interesting thread as I just did some research on tire pressure too.
My example is load range "E" tires on my E450 class C. The tires themselves call for max pressure of 80lbs. The door sticker shows 75 front, 80 rear, and that worked "OK" with the Michelin tires I had and I never questioned the pressure. It rode like a truck and I guess that is what I expected.
I recently bought a new set of Yokohama load range "E" tires with the same tire pressure maximum stamped on the tires and I was completely disappointed in my purchase. The RV wandered all over the road and was very difficult to keep in my lane... I'd never had that issue before. I decided to see if anyone else had similar results.
My research lead me to this chart...
Michelin Tire pressure ChartLooking at the chart shows that Michelin recommends varying tire pressure based on actual weight carried. Well dang I thought... I'm sure I'm not anywhere close to the maximum tire rating so off to the truck scales to verify my weight per axle.
Yikes! According to the chart, I was WAY over recommended pressure. According to the chart I should be running 45 lbs front and 60 lbs rear for my actual loaded RV weight so...
I've compromised a bit and am running over chart recommended pressure 65 rear and 50 front. Yes, I know the chart is for Michelin and not Yokohama tires, but Yoko does't offer a comprehensive pressure chart that I could find so I'm taking some risk I suppose, but the RV drives and rides better than ever, and we operate in the summer Nevada heat over 100f often so I'm confident I'm not overheating my tires (checked with temp sensor).
My conclusion is knowing how much your RV actually weighs will effect the actual tire pressure you should maintain.