Amphours are amphours whether they are from a 6 volt jar or 12 volt. Wired in series battery voltage is added together and amperage remains same, and with paralleled batteries voltage is constant and amperage is summed up.
Most 6 volt GC batteries are roughly 210 to 225 amphours, and most 12 volt batteries range from about 85 to 115 amphours depending on group size. Under most circumstances, a pair of 12 volt batteries will have very similar amount of amphours as a pair of 6 volt batteries.
The difference lies in their construction and design. I've had both 6 and 12 volt set-ups and found that our pair of 6 volt GC batteries are proving to be more resilient when deeply discharged and are better capable of taking the abuse of camping off the grid.
Our current set of 6 volt GC2 Interstate batteries purchased from Samsclub are still providing good, reliable service going on 5 years. I had good success with our 12 volt setup albeit with shortened longevity. With either choice how they are charged and maintained makes all the difference.