My camper two campers ago was a chassis mount 10.5 Travel Queen on a 1975 C20 chassis in which I installed a Detroit in the 14b. It worked exactly as expected/hoped. In my opinion there is zero downside to a Detroit in that situtation, other than cost. It spent most of its life off road in the 1990s and it was a beast for 2wd. Loved it. Wouldn't trade that time for anything.
Prior RV was a 1984 era 24' class C which had a "G80" a.k.a. "Gov-Lock." GM's version of auto locker. Never went in anything rough but the overhang and width were such it might as well be open because if it went too far off the beaten path it would be stuck regardless of drivetrain. Never spun enough to engage the G80, not sure it even worked.
Current rig 2019 Ford based C. It is too pretty, and I'm too old, it will likely never go off road. Maybe gravel road...someday. All I know about is diff is it is 4.56, it is probably open and I'm OK with that.
My point is if you are going to use it, get a Detroit put in. No down side in my opinion, work great mud snow sand, 100% reliable and bulletproof.