Hi Gator,
Statistically speaking there are 1/2 the number of cells in two six volts of similar capacity to 12 volts. Wiring can't be done in an unbalanced manner so it is "goof proof".
There are some disadvantages as well. Such as no redundancy, greater voltage drop for a given load, and inability to run extremely high demand loads such as a 3000 watt inverter. Wiring needs to be done in a balanced manner so there is one optimal way to wire. Most battery installers are NOT aware of this need, which I believe leads directly to shorter life spans for twelve volt pairs.
The absolutely ideal battery bank would be six large two volt cells. Be prepared for "sticker shock".
A good bank for me would not suit the OP very well. Banks should be designed to "fit" the camping style of the user.