Best way coolers work is, if possible, have cooler intake air from warm or sunny side. Let some of the exhaust air exit where you want to to cool. Ie if cooler taking air in from middle of RV let some exhaust in each end of the RV.. if you want just center to cool let intake be from one side and exhaust out the other. You need one square foot of exhaust opening for every 1000 cfm of intake are, or fraction there of. I would never run acnd and cooler at same time when you are exhausting air like you must to get max cooling avail from a cooler. Kind of like trying to cool the great outdoor.