Had a 2012 F150 w/5.0 and 3.73 gears and now the 2016 5.0L w/3.73 gears.
The 2016 is a tow beast. Tons of torque and power anywhere I need it. I also get great mileage towing around 11 mpg and great mileage when not towing about 18.5 mpg mixed and up to 22 mpg expressway.
While many like the Ecoboost, I really like the 5.0L and why I got it in the 2016.
The 3.73 gears can be found and offer a lot more towing capacity and torque multiplication. The 3.73 diff is larger at 9.75" opposed to the 3.31 and 3.55 diff that's 8.8".
When saying the Tundra is more reliable is debatable. What I've seen complained about in the past, is that when these trucks are used for work, they don't have the reliability you would hope. They do better for grocery getting. They also have lower payload than Ford or GM.
Myself, if I could deal with the Tundra's lousy fuel economy, I'd then just get a F250 6.2L. Since I need some efficiency to daily commute, the F150 5.0L fits my needs.