We're a young family with two toddlers (2 and 1 y.o), so for us getting a van was a no-brainer. Pick-ups or 3/4 ton SUVs (Suburban/Excursion) offer nothing close to van's room. I removed the extra seats and added a conversion van power sofa. You can't beat the room inside, the kids can sleep on the power bed, go potty, have lunch, walk around, etc.
Vans are awesome towing vehicles. Based on pretty much identical frame and drivetrain as pick-ups, they tow very well.
We've been towing our 2004 Keystone Springdale 37BH with a 2006 GMC Savana 3500 6.0 liter 15 passenger van. Currently has 205k miles, but it never towed before I purchased it for less than $4K. The manufacturer's tow limit for the van is 10,000 lbs, and our trailer weighs 11K or 12K lbs. Our total weight on CAT scales is 18,200 lbs.
The trailer is 39' long, and our total length is 60'.
We have the biggest possible tow vehicle and one of the longest travel trailers. We fulltime, so having two separate bedrooms and a living/play room was very important. We're a bit over the weight limits but I could care less really.


I use a weight distributing hitch. I also have an anti-sway bar but in 2000 miles I never used it. The trailer always follows straight and never wiggles. Perhaps it is due to larger frontal area of the van, but I never had any swaying issues.
The van has been equipped with a 10k lbs hitch, trans cooler, towing mirrors and a brake controller. I can comfortably maintain up to 70mph on a highway. We averaged 7.8 mpg hwy when towing.
However, when we were in Asheville NC area, extremely hilly terrain (9% grade), our combination could only maintain 35mph in the rightmost lane and also began to overheat (no electric fan here, the fan is viscous coupling on water pump), so I turned both interior heaters on full blast and it helped a lot. The uphill was for only may be 10 miles, so no big deal.

Overall we're extremely happy.