If you are going to drive in 100 degree heat for any distance the ST tires are not a good choice, although they may last for one or two trips. For long distance driving in summer temperatures and full loads you need LT tires. Plus LT tires can be driven at highway speeds (70+) without damage or overheating-the main cause of tread failure/blowouts in ST tires.
In high heat and under normal 5er load (8500lb in a 12000lb rated trailer) I have had ST E tires blow out in less than a day crossing AZ and CA desert at 100 plus temperatures. The tires were at the correct pressure and were less than 2 weeks old when I left Tucson. Two blow outs by Needles and another going through LA--although that might have been the potholes on I-10. Changing a tire on US95 at 110 degrees is no fun and doing it twice was down right irritating. Switched to LT tires and have not had a single blowout in 7 years.