I don't want to turn this into a Ford 6.0 liter discussion, however I have 2006 f350 with the 6.0 it is completely stock and with no chipping. I got 68K on mine and have had the same thoughts as you about doing the preemptive "bullet proofing" I have updated and completed all the little things, like coolant, blue spring, trans pan upgrade etc. and figure Ill drive it until we get to the point that the oil temp and coolant temperature differential is greater than recommended and go from there.
My camper is a Lance 1130 and have done a few tweaks to the suspension like upgraded sway bars that help significantly and so far I am happy with the performance and handling
good luck with yours