Ram 2500 6.4 vs F150HD 3.5 Eco as a daily driver

I think you will find the 2500 gets quite a bit worse fuel mileage tootling around town empty, and rides like a truck with no load to calm it down. The 1500 should get far better fuel mileage around town and probably equal or better towing within it's capacity, and will basically ride like a car. The main difference between them may be load capacity and top end towing ability. If you tow within the capacity of the 1500 it would probably be my choice for a daily driver.