I see benefits for with and without, and I'd like one of each type. Since I can't have both, though, I prefer one with slides. For our family, the pros of slides definitely outweigh the cons. I say this after having to spend a couple grand to fix one of my slides and rebuild its floor after undetected water intrusion. They're still worth it to me.
One more thing:
Definitely equip your slides with good topper awnings. I believe they will save you much more than they cost. I'll never go without them again.