We went from a bumper pull toy hauler to a truck camper with enclosed trailer in tow a couple of years ago. The size and number of our toys increased and we did not want to go to large tow hauler that would also require a bigger truck and limit our access to tight locations. We were able to keep overall length and GCW the same but ended up redistributing living/garage space and weight.
As posted earlier, the hardest part for us the wet bath since there is no place to hang wet gear when we do not take our enclosed trailer along on a trip (have clothes lines strung inside). We live in an area that gets rain almost 300 days out of the year which means you you need a "mud room" whether that is your bathroom or an enclosed trailer.
We also find the lack of a sofa or comfortable seating an issue with the TC over our toyhauler. We have adjusted our lifestyle to fit the booth dinette, but it will be something we will weigh in next RV.
We dry camp for extended periods and find the capacities are fine for three nights, but we want more when away longer. We rectified this by adding fresh and gray tanks to the trailer and hauling extra LPG in there as well. Many of our trips are to off-road locations which will get you dirty by the end of the day and require a daily shower. We also have dogs that stay in the TC while we are away. Depending on the time of year, we may run the AC on the genset or heat the whole time we are gone and when we return.
I also run 19.5" wheels on my truck. This due to the combined TC and trailer tongue weight on the rear axle. If I was not towing 7000 lbs behind me there would be other tire choices on stock rims that would give me 7500 lbs of capacity.