it's a great route without heavy traffic. Use the loop at Eagle Pass to avoid the downtown area.
Del Rio doesn't have a loop, but when you get to 90, just cross over it and continue north on Bedell Ave which is not good, but better than taking 90..stay on it to 17th Street then go left over to 90. Plenty of rv parks on that side of the city.
There's a state park up the road a few miles north of Comstock. There's a great overlook of the Pecos River canyon a few miles north of the state park and you can overnight there if you want.
At Langtry, there is a goverment memorial to the infamous Judge Roy Bean, with a museum..good place for a brief rest.
Distances become longer between good fuel stops, so if you need fuel, Sanderson is best choice. After that, you have to go to Marfa.
If you are ready to stop, there is a rest stop about 6 miles east of Marfa that offers a viewing site of the famous Marfa mystery lights, and we have seen them and so they do exist. Lots of folks overnight there.
If you are so inclined, this is a good place to turn north. Go up through Ft. Davis and see the old fort. There is a state park Davis Mountains State Park there. And the McDonald's observatory offers "star parties" (search internet) and then the road from there up to I 10 is scenic... a little twisty for a short way, then smoothing out again.
That said, be sure and keep a watch on the weather forecast because this area of west TX is subject to sleet storms with plenty of good dry weather in-between. If you run into such a storm, it will likely be done with in a day, so just stop and wait for the road to clear.
