I just drove it today (F150 pulling a 26ft TT). Surface condition of the road was in great shape the entire way (that I recall). Road is generally tight, twisty and can be narrow (lacking a proper shoulder for much of it). A good climb coming out of Pemberton with some switchbacks. It was relatively slow going for me, but the traffic was light on a Tuesday morning/afternoon in early August. No services for that stretch, but definitely places to pull over.
Overall had no issues and wouldn't think twice about taking a Motorhome w/toad or larger Fiver (though I've never driven either of those). It's just not going to be fast.