FWIW, the best mileage I ever got with my '02 D'max was right at 23 mpg on a trip up to Cortez CO in '14. I had a 14 cu ft chest freezer in the back, tucked up against the back of the cab. I started off at 65 mph and DW said I was driving too slow (a change!) so I ramped it up to 75. Temps through N AZ and SW CO were in the high 20's to low 40's. I consistently saw 21-23 mpg the whole trip. Surprised hell out of me and I can only attribute it to having the freezer in the bed and how it affected the aerodynamics. My previous best mpg was right at 22, down near Patagonia, when we were simply putzing around and touring some of the S AZ wineries. :-)
Lyle