A couple of years ago, I did a detailed cost analysis of purchasing, maintaining and selling a F250 Lariat crewcab with the 6.2 gas vs. 6.7 diesel engines. I researched dealer cost/retail prices on front end and depreciated the trucks according to NADA and KBB used truck prices. Maintenance was also estimated.
If I sold a 6.2 truck at 10 years and 120k miles, the total cost to ownership would be just over $3,000 cheaper than buying, maintaining and liquidating a diesel truck.
The prices of "heavy duty" light trucks is up dramatically since that time,however. If I was buying a SuperDuty today, I'd be ordering a F350 dual rear wheel diesel, but with the XLT cab and the $795 appearance package. By not going Lariat's leather seating, you can pickup most of the cost difference in the diesel option. It's still a nice truck, but it's also not in "The $60's."