Four years ago we left the Rochester area on the 5th of February. We didn't have any major plans or reservations. So we just watched the weather looking for a break. Due to all the storms that we moving up the coast that year, we headed more inland using I81, I77. I26, then finally I95.
Even tho we had to dig out from under 18" of snow, we had none once we hit the road.
We actually un-winterized while hooked up at the house, loaded we everything we needed and set the furnace at 50-55 to keep things from freezing. The first couple of days we traveled with the furnace on at that low setting.
Now we leave in early October and don't return till May.
Good Luck and just take it slow and easy if you hit bad weather.
2018 Chevy 3500HD High Country Crew Cab DRW, D/A, 2016 Redwood 39MB, Dual AC, Fireplace, Sleep #Bed, Auto Sat Dish, Stack Washer/Dryer, Auto Level Sys, Disk Brakes, Onan Gen, 17.5" "H" tires, MORryde Pin & IS, Comfort Ride, Dual Awnings, Full Body Paint