There are more disqualifying factors than a well maintained 460 engine and E4OD transmission. They should be serviceable well beyond that 130,000. Kevin ID's the deal breaker: Leaks!
We had a much older E350/460 coach and the engine was solid at a little over 100,000 when we sold it for other reasons. Specifically we didn't want to continue climbing into the cabover bunk.
Also, a number of OP's here have ex-rentals they bought with high miles and are getting good service out of them.
I'd rather have 100,000 miles of careful use and maintenance on a "Love Coach" than 10,000 miles of abuse and neglect on "Priced to Sell."
Love Coach? You'll recognize one. Clean, owner manuals filed, maintenance receipts, little upgrades here and there, tires in date, maybe selling because they traded to new or maybe can't use it any more.