Check my sig. Goes that way every year. Mom lives in SF, I go up through Chama to Pagosa Springs, then 160 to Durango. You should go up through Silverton and then to Ouray. Just steep and slow, and the views are amazing. From just SF to Mesa Verde is very easy through Chama.
Through Cuba isn't bad, takes you up through Farmington and 550 is actually closer to Bernalillo than SF. This route is flatter and less scenic.
Bill
2013 Fleetwood Discovery 40G
TOADS: 12 Jeep JKUR Wrangler, 16 Cherokee Trailhawk, 15 Grand Cherokee, 13 RAM 1500 Longhorn (not a toad) American STEEL = American profits
RET USAF MSGT (26yrs) and still DoD ATC.
DW,DS,DD in the MH w/Westley the killer PUG!