Finding the problem yourself is going to depend on your mechanical skills. Couple of items to check before heading to Ford.
1. Check the air filter. Although your coach is new enough early F53's had a problem with the air filter getting water soaked in heavy rain and restricting air.
2. If you have the tools, check your fuel pressure. The in tank fuel pump could be failing or the fuel filter is clogged. Checking fuel pressure is a lot easier than dropping tank or buying filters that you might not need.
3. Since the V10 uses coil on plug for spark you could have problems with spark but I suspect the ECU would throw a code for a misfire but I might be wrong. Not sure how to test other than buying one wire and swapping to find the problem.
4. Another problem could be with the catalytic convertor clogged restricting exhaust flow but not sure how to tell without removal or replacement.
5. This one is a bit of a log shot but you could have a brake calibrator dragging. Use a none contact IR thermometer to check the disk temps next time you're out. The disk should have about the same temps left to right. Front to back might be different.
Good luck.
2006 Hurricane 31D built on a 2006 Ford F53