Using Michelin's chart:
225/75/16E
65 PSI Single (Front) equates to the GAWR of the 4600# front axle E450 used through 2007 (chassis year)
and
75PSI works out to GAWR of the 5000# axle used from 2008 up.
80 PSI = MAX. Most likely over inflated for most needs.
ALL "E" load class tires are certified by DOT for the same load rating at PSI.
To get the exact PSI for your vehicle ypu need a 4 corner weight the consult the charts.
You can also call the tire manufacturers with the 4 corner weight and they will give you the PSI that you should be running.