Have the vaccination. Then consider the viral load in the locations you wish to visit. Plan the route accordingly.
There is a clear case that high population centers (cities) have more transmission than lower population.
Take precautions such as using disposable gloves when buying fuel.
If you stay in campgrounds, sanitize as much as possible.
If possible, have food delivered to your RV rather than going into stores.
Regards, Don
My ride is a 28 foot Class C, 256 watts solar, 556 amp-hours of Telcom jars, 3000 watt Magnum hybrid inverter, Sola Basic Autoformer, Microair Easy Start.