Obviously every safety aspect of a tire is important. Be sure to check the load rating with the (C or D) tires that you may purchase since there are variants within the those load ranges. Anywhere from 103 to 108 which can be up to 600lb or more difference in load carrying. This, I didn't know until having a long talk with the tire shop. They were very versed in trailer tires.
We went to a 215 over the 205s that were on ours to gain around 600lbs (I believe) in carrying capacity. These new tires are .6 inch wider and just under an inch taller. Safe for operating as they exceed mfgr ratings and fit perfectly on the stock rims (they must to be safe). They should run cooler and we can carry 8200lbs on a TT that maxes at 7488 so they'll never really be "tested" to their max. Yeah, we went well over and above. The cost was the same as OEM Endurance tires (205's) and we have a little more piece of mind.
All that to say "you have options". Be sure to do your research and you can even reach out to the manufacturer. And of course there's plenty of wisdom here from those who've been in the game for decades.