I actually had Vision 81 wheels wrapped in Michelin XDS2 245/70r19.5 tires for two or three years.
About a year ago, I swapped them out for Method 305NV HD wheels with 295/70/18 Cooper Discoverer STT Pro tires. There was finally an 18-20" wheel on the market with something more than the 3400-3750lb capacity listed on all aftermarket wheels I was finding.
I don't have a truck camper but instead have a 15.5K gross fifth wheel with around 3200lb pin and a 51gal aux tank in the bed. I'm in DRW territory but have a Kelderman 4-link air ride and the aforementioned wheel/tire configurations to handle the load.
Moving from the stock tires on my truck to the 19.5s was a night and day difference. The increase in stability was amazing - the change to the Method wheels was less obvious for me. Sure, there is a difference, but they're 85% as good while loaded while also being 85% more versatile. Or something along those lines.
There is a certain peace of mind that came with the 19.5s, but I really don't feel all that much difference since going back to LRE tires on the Methods. I've run them for about a year now as a seasonal RVer and they have met my needs very well.
So in summary, I've run both and while there is an improvement in stability with the 19.5s over the Methods, it is fairly minimal compared to the improvement from factory tires to the Methods with the larger tires (or at least STT Pros) running at 80PSI.
All that being said, I'm currently tossing around the idea of trading for a DRW. It has nothing to do with me feeling unsafe in my current rig, but more the legality of it - we're going to full-time, and I'm leery of taking a deleted, overweight truck all over the country. I'm still very tossed about this because I am happy with the way my truck handles the load and love how versatile it is, even off-road, when unloaded. I'm somewhat concerned that moving to a DRW with traditional leaf springs will be a practical downgrade from what I am currently running, but that's a whole separate topic.
2000 Country Coach Magna 40',
4380W solar, 22.8kWh LiFePO4@48V, 450AH AGM@12V
2020 Jeep Wrangler Unlimited Rubicon 2.0T, cloaked on 37x13.5s