x(how many) replies above. I use two kinds of tape when installing the anode rod in our Suburban SW6DE water heater:
1. Teflon Tape on the Threads, applied by winding it around the threads as if by tightening the plug.
2. Electrical Tape around the Head of the Plug. Then I can force it into the Socket that I use to tighten it with. Then, with an extension in the socket, I position the anode plug in the socket so the anode and rod and the extension are lined up straight. That makes it easy to get the plug threads started into the hole in the tank.
Before, I tried to stick the anode into the thank and align the threads with just my fingers on the head of the plug. What with the weight of the anode inside the tank, the angle of the hole, and other parts of the heater near the hole, I found it difficult. Using tape, socket, extension, made it very easy.
Call me Anal and you won't be the first. I'm also risk averse and really don't want to wrench on a cross-threaded plug, thinking I'd started it right.