We have a 32'2" Jayco Greyhawk 31FS on a 2008 Ford E-450 Chassis. The frame is stout from front bumper to rear bumper and is rated to two 5000 lbs. As j-d mentioned, the turning radius is not so great for making u-turns, but I've never had an issue making any other turn.
Ours is the only Motorhome I have driven, so I can't really compare how our Motorhome drives compared to smaller Motorhomes. I have read a lot of horror stories on here about how folks had have white knuckle rides in their Class C. That is not the case with ours. I am comfortable driving ours all day, with the longest single day trip being 900 miles.
-Michael
