We are looking at a "new to us" Itasca Horizon 40'. we have two to look at. Both have the same floor plan however one has the 400 hp the other has a 350. This would be our first diesel motorhome, is ...
I have the ISL 370 HP in a 41 foot Dutch Star with four slides, usually at maximum weight, pulling a Jeep, and I go anywhere, on any grade with it, and get 8 mpg with it in good conditions. I may be heavier than the coach you are looking at with the 350. You could probably be fine with the 350. But, like others, why not go a bit larger unless information on mpg etc. is very negative on the 400.