I bought a '94 Bounder in '04 and drove it a couple years before discovering it had a manifold leak. One of my blog readers pointed out the black soot he'd spotted on one of my posted engine pictures.
I checked carefully and couldn't see where the leak was causing any other issues so I kept driving it that way.
It was another year before I made it down to Mexico where I had the broken manifold stud removed and replaced by a specialist ($50 USD). Also replaced all the manifold bolts with new, along with installing a high temp manifold gasket. Did some other top of the engine maintenance at the same time. That all came to under $300 USD.
I'm not suggesting you should drive your RV if you have a manifold leak, as each case is different.
Another weird 'rattle' noise I had coming from the engine compartment turned out to be the vacuum pump...the pump that creates the vacuum needed for cruise control and the dash comfort controls. It rattled for several years before it finally went bad. It wasn't until I lost both cruise control and dash comfort controls at once that I found it back near the engine mounted on an inside frame rail...still making the rattling noise only much louder.
Good luck. If you're close to Mexico though, they have great mechanics down there.