I-10 California to Florida.

how far off I10 are you willing to go.
How much time do you want to spend.
I can recommend beaches were you can park 50 yards from the water BUT you have to travel off I10 about 25 miles or so,
The Blue water highway along the Louisiana gulf is nice if you have a few days.
NEED MORE INPUT FROM YOU

If you are in Oregon, Hearst Castle is a must see. I like architecture so Frank Lloyd Wright homes are always at the top of my list. Hollyhock house in Hollywood is neat to see.

It depends if you are going to swing south or go midway through the USA, Las Vegas is fun and the Las Vegas Motorcoach is the best place to stay. Many restaurants to pick from.

Frank Lloyd Wright has a compound called 'Taliesin West' in Scottsdale, AZ, it was an architectural school/home for he and his students. Biosphere 2 (earth is Biosphere 1) is also a must see in Oracle, AZ.

You will have a very full schedule!

MM.