As long as you keep the belly warm and keep some heat going inside as well (open all the cabinets where any water lines might be located) then you will be fine. It doesn't need to be 65, but around 40 is pretty safe. The water tank itself is unlikely to have issues as the warmth of the water will help keep temps more stable in the belly area. IF, IF, you have NO exposed sewer drain pipes or these pipes have no fluid in them then they are OK at any temperature but once you flush you will have to keep all drain pipes exposed to those kinds of temps warm as well. Once you get away from the 17's and into the 35's then you are good to go for most anything you like.