Nashville to Atlanta

Haven't made the trip to Florida on the route through Atlanta in a long time. It has always been down 65 for stopover in Gulf Shores. So right after xmas we head south and take 24 to 75. Is there any thing we should know about roads and weather. As I recall there were several long pulls in the mountains around Chattanooga and Look Out Mountain but in those days I was driving a 1983 Winnebago Centauri with a 4 cylinder diesel that got 70 off a cliff. Cruised great at 55 and got 23 miles to the gallon but it worked in steep terrain. I am driving a Winnebago Vista (gas) 30T 2012 and towing a 2004 Jeep Grand Cherokee instead of my Smart Car this trip. Appreciate any warnings or advice on this stretch from those who are more current.