Most toy haulers have a 4' tongue and are wide 8.5' (lighter ones are 8' wide). Tongue weight will be very heavy even when unloaded since it is designed to carry your heavy toys in the rear while still being stable. You may have to upgrade your receiver to handle this weight, but the truck is capable of towing any of the bumper pull TH's on the market.
When I had a 22' TH (26' actual) behind my truck, I was 45' nose to tail overall length. This was a very easy length even in tight state campgrounds although the height and width did require some tree pruning at times. If you plan on heading out to the desert, trees are not issue (we will be out in Needles, CA in less than a month).
Navigating through town will be your biggest obstacle. Avoid tight driveways or ones that have tall curb height. When making turns, try to choose the outside lanes and remember that the rear does swing out because of the pivot point on the rear axles (less of an issue with a TH than a TT because the axles are farther back).