Are you full-timing? Or do you have a permanent home. IMHO, I think it's easier to travel alone if you have a good support system waiting for you at home. If you're full-timing, I think it makes it more difficult since you're always moving around and having to start fresh with each move.
For me, if it's more than a week's trip, I think mixing it up is a better option. When I travel (versus simple camping), I try to plan time around people - sightseeing, etc. for part of the trip.
For an RV road trip, I'd suggest boondocking for a week, then maybe hitting a festival for a weekend, then another week of boondocking. Festivals are great because there are tons of opportunities to chat with people. There are so many festivals out there and many are in areas perfect for RVing.