I am around 2,800 rpm at 65 in my '78 GMC one ton SRW standard cab pickup with a 4.10 rear. Right in the power band, and it does great. Use it to pull a car hauler with a car, GVW of trailer is 7,000. Not much wind drag like you will have with a travel trailer though. Mine is stock 454/TH400 combo., 250 horsepower and 395 ft. lbs. torque, factory dual exhaust and catalyst exempt due to it's 9,000 GVW rating. Honestly, I think you would be fine with either gear, or split the difference and go with a 3.73. Before I got the new tires for the GMC, I used a friend's F-350 to move a car here from out of town. His truck is a 1996 crew cab long bed SRW with 460 and 3.54 gears. His truck did the job well, but was noticeably slower to accelerate than mine carrying the same load. In it's defense, the F-350 is heavier than mine due to being a crew cab, but the difference is very noticeable.