US-2 has already been mentioned.
There a lot to see along I-40. In Amarillo, there is
Palo Duro Canyon State Park and the
Big Texan on Old Route 66. In New Mexico,
Tucumcari still has dinners along Historic Route 66 and numerous murals painted on buildings plus other attractions. Santa Rosa is another Route 66 town and has the
The Blue Hole and
Santa Rosa Lake State Park which has a nice campground. In Albuquerque, the
Pueblo Cultural Center and
Petroglyph National Monument are worth visiting in my opinion. In Grants, there is the
Mining Museum. Just South of I-40 going West from Grants are
El Malpais National Monument,
El Moro National Monument and the
Ice Cave and Bandera Volcano.
Acoma Sky City is said to be the longest occuppied location in the U.S. They give tours of the pueblo and there is an RV park next to the casino.
East of Flagstaff along I-40 are
Petrified Forest National Park,
Meteor Crater and
Homolovi Ruins State Park. You can stand on the corner in
Winslow Arizona.
In the Flagstaff area are
Sunset Crater National Monument,
Wupatki National Monument, and
Walnut Canyon National Monument. Sedona/Camp Verde/Cottonwood are about an hour South of Flagstaff with
Montezuma Castle and Montezuma Well National Monuments,
Tuzigoot National Monument,
Palatki and Honaki Ruins,
V-Bar-V Heritage Site,
Verde Canyon Railroad,
Fort Verde State Park,
Cathedral Rock,
Gold King Mine,
Jerome State Historic Park in the area.
And then there is the Grand Canyon.
In the East, I-40 will take you to Memphis, Nashville and along the North edge of the Great Smokey Mountains to the East coast in Wilmington, NC.
US-60 runs South of I-40 in Arizona and New Mexico and would take you to some of the more out of the way places like Pie Town, the Very Large Array, Fort Sumner and Palo Duro Canyon.
US-64 runs from near Monument Valley in Arizona across Northern New Mexico. It will take you to places like Farmington, Chama, and Taos and continues on to the East coast in North Carolina.
US-50 goes coast to coast through the middle of the country. US-54 and US-56 provide alternatives through different parts of the plains states.
US-20 is a more Northern coast to coast route and is the one chronicled by John Steinbeck in "Travels with Charley".
US-40 and
US-30 offer two more possible coast to coast routes.
North to South the
Great River Road (US-61) follows the Mississippi River and goes through or near many great places to see.
In the mountain states,
US-89 and
US-191 will take you to more National Parks and natural areas than just about any other roads.
