I tow both 4-down and with a dolly depending on the situation and the car we want to take. There is no doubt that 4-down is easier. And there might be issues with what to do with the dolly at times.
However my experience is that the type of trip will define how much that really matters.
If its a trip where we are going to go to a destination and stay for several days or longer, its not much difference because we don't need to load and unload the dolly very often.
If its a trip where we move often then the 4-down approach is much more convenient to hitch and unhitch more frequently.