No man... a loose wire will not kill an idle battery. It can make it not charge well when the engine is running and that will make it drain.
The best battery to jump a late model Duramax from is the passenger side one.
That’s it’s “primary” battery. Yes, they are both connected in parallel and it will work either way, but the passenger side has the most direct connection to the starter. The driver side battery goes through longer cables before it reaches the starter.
If you jump from that side there’s more resistance.
Like I said either side will work, the passenger side will work a little bit better. But not much. Not enough to stress over it if it’s inconvenient to reach the passenger side.
Another thing you can do is hook up two sets of jumper cables. That reduces the resistance and flows more current. It’ll start sooner that way.