There are several options since Spruce Knob can be accessed from different areas via different roads. I agree that the Seneca Rocks area is nice. Seneca Shadows Campground is within site of the rocks. There is a walking trail to the top of the rocks. You can also get to spruce knob from the area of the Cass Railroad which is a nice ride to the second highest point in WV, Bald Knob. The town of Elkins is close to all of these places. There is a scenic train that leaves out of Elkins. I stay at East Fork Campground in Durbin, it is a small private campground on the East Fork of the Greenbrier River. This is the home of the Durbin Rocket, another scenic train. There is a primitive campground on the road to Spruce Knob. It is close to Spruce Knob Lake. If it is cloudy or rainy you will not be able to see anything from the top of Spruce Knob and the drive is long from any direction. So choose a nice clear day to make the trip to the Knob.