I've had 2 instances when it would have been nice to have had a TPMS. Once a tire stem cracked and I didn't realize it until the next stop when the tire had about 10 psi of air in it and was hot as a pistol. It didn't blow but easily could have due to heat buildup. The other time I had a tire disintegrate and didn't know it until a passing driver apprised me of the situation. I did have 1 catastrophically fail, but I don't know that a TPMS would have warned me in time to have done any good. That one cost me damage to the toyhauler and I heard it loud and clear.
I now have the TST 507 system and I just look at it as fairly cheap insurance. If it saves me some damage to my toyhauler it's worth it.