I've felt a flat dual on a truck as an imbalance, just like a tire that was out of balance.
When stopped (fuel, break, ect) I'll reach under the fender and just push sideways on the inner tire; if it gives way it is low on air. Or you can stand behind the truck/trailer and look for a tire that has an excessive bulge when sitting on even ground.
2005 2500 Cummins/48RE/3.73, QCLB, 4wd, BigHorn, Edge Juice w/ CTS + Turbo Timer,Transgo Shift Kit ISSPro Oil and LP pressure gauges, GDP 20/2 filters, Custom Diesel Steering Box Brace
'10 Forest River Shockwave Toy Hauler 21'
Honda EU3000I Genny