Up is easy, just gas it and try not to get caught behind the real slow ones. You will want the RPM's up 3500 to 4000, more wont hurt it.
Down is a bit harder, but I'd try to find a gear that would hold me around 35 to 40 with minimal brake. Whatever gear and speed you came up would be a good place to start going down, maybe even slower.
2018 Silverado 3500 DRW
2011 Montana Mountaineer 285RLD