How much space above the rails do you have and how thick is the frame for the cover?
If you are trying to squeak by with 4" above the bed rails and the cover frame is 2" thick, expect it to be trashed after the 1st trip.
If you have a solid 8" above the bed rails and the cover frame is 1/2" thick, it should be fine unless you take it on really uneven surfaces.
Without knowing those two dimensions, anything else is a wild guess.
Tammy & Mike
Ford F250 V10
2021 Gray Wolf
Gemini Catamaran 34'
Full Time spliting time between boat and RV