I've seen some people do it, but you're going to severely restrict where you can park. 42' plus 22' is 64'. There's not a lot of pull-thru spots that long and then you'll need room for whatever you unload from the trailer to drive.
Have you thought about backing that thing up? My DP has good mirrors, but 22' of enclosed trailer is going to put a lot of area into a blind spot. It won't be like looking over the Jeep with the mirrors.
I'm making the assumption that you'll have a car of some sort in the trailer, have you tried securing a car in an enclosed trailer yet? It's harder and more time consuming than you think.
Bottom line, I wouldn't do it. We considered an enclosed trailer when we got a DP and I soon dumped the idea. It's one thing if you have to use one to haul something specific like a race car but other then that, I'd stick with the Jeep back there and you'll do just fine.
Bill
Nodwell RN110 out moose hunting. 4-53 Detroit, Clark 5 spd, 40" wide tracks, 10:00x20 tires, 16,000# capacity, 22,000# weight. You know the mud is getting deep when it's coming in the doors.
